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Postdoctoral Research Associate - Orthopaedic Surgery - 49942
University of Washington in Seattle, Washington
Date Posted 12/14/2020
Admin-Laboratory and Research
Employment Type FullTime
Application Deadline Open until filled

Post Doc Instructions

Please do not submit an application to this posting.  To apply for this postdoctoral research opportunity, follow the directions below in “Applicant Special Instructions”.

Department Name/Job Location

This position is in the Department of Orthopaedic Surgery.  This position is for the Medical School Campus.

Essential Functions

The Orthopaedic Research Laboratories (PI: Dr. Audrey McAlinden; Co-Investigator, Dr. Farshid Guilak) in the Department of Orthopaedic Surgery at Washington University in Saint Louis, has an opening for a post-doctoral research associate. The post-doc will work on an NIH-funded study to investigate the function and mechanism of specific long non-coding RNAs in regulating stem/progenitor cell differentiation toward the chondrocyte lineage. The long-term goals of these studies are to determine new mechanisms and/or identify novel targets that can be exploited for future approaches to engineer new cartilage tissue or ameliorate cartilage breakdown resulting from conditions such as joint trauma and osteoarthritis.

You will join a multidisciplinary orthopaedic research laboratory, which is part of the Musculoskeletal Research Center ( ). The post-doc will be based in the lab of Dr. Audrey McAlinden ( ) and will collaborate with the co-investigator of this project, Dr. Farshid Guilak ( ). There are excellent opportunities to interact with other cartilage/bone biologists and biomechanical engineers in the Center, as well as PIs in basic science departments at Washington University specializing in RNA biology and stem cell differentiation.

Required Qualifications

  • Ph.D. degree in the field of molecular/cellular biology, biochemistry or a closely-related field.
  • Strong background in a range of molecular biology and RNA-based approaches (e.g. cloning and construct design, shRNA techniques, RNA pulldown assays, FISH, RNA-Seq analysis).
  • Previous experience working with primary stem/progenitor cells and differentiation assays.

Preferred Qualifications

  • Some experience in musculoskeletal research would be an advantage.
  • Knowledge of other specialized techniques, such as ChIRP-Seq, proteomics and CRISPR technology is advantageous.

Salary Range

Base pay commensurate with experience.

Pre-Employment Screening

All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. Current employees applying for a new position within the university may be subject to this requirement. The screenings will include a criminal background check and, as applicable for the position, other background checks, drug screen, employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.

Department Summary

Whether suffering from a sports injury, hip pain, back pain or any musculoskeletal condition, Washington University Orthopedics provides a full complement of comprehensive orthopedic services to meet the needs of every patient. Combining the best in both inpatient treatment and outpatient care and rehabilitation, the practice is nationally recognized for outstanding orthopedic care, innovative research and advanced professional training. It is ranked among the best orthopedic practices and holds the distinction of being listed on the Honor Roll by U.S. News & World Report. The practice is considered an innovator in both conservative orthopedic care and minimally invasive microsurgical techniques. Affiliated with Barnes-Jewish Hospital and St. Louis Children’s Hospital, Washington University Orthopedics has the unique ability to offer inpatient treatment for the most challenging cases within a top-tier academic medical center as well as outpatient surgery and care across the St. Louis region in Chesterfield, Town & Country, South County and the Central West End. The practice offers expertise in ten orthopedic subspecialties – foot and ankle, hand and wrist, hip and knee, cancer, pediatric and adolescent orthopedics, physical medicine and rehabilitation (physiatry), shoulder and elbow, spine (including scoliosis), sports medicine and fracture care/trauma. The orthopedic specialists are dedicated to providing safe, compassionate and family-centered care for both simple and complex orthopedic conditions. Because of the skill and experience of the doctors and staff, it is the official medical provider for the St. Louis Blues hockey team, Washington University varsity athletics and several local school athletic teams. Washington University Orthopedics brings world-class care to patients from all ages and walks of life in St. Louis and the surrounding communities.


This position is eligible for full-time benefits.  Please click the following link to view a summary of benefits: .

Applicant Special Instructions

Applicants should apply by sending a cover letter, CV, and the names of three references via email to:

Audrey McAlinden, Ph.D.
Associate Professor of Orthopaedic Surgery
Washington University School of Medicine
St. Louis, Missouri USA


Applications will be considered until the position is filled.  Inquiries may be made by email. 

General information is available at , and .

EOE Statement

Washington University is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, genetic information, disability, or protected veteran status.

*Please mention to employers when applying for this job*
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