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Post Doctoral Fellow
University of Kansas Medical Center in Kansas City, Kansas
 
 
Apply
 
Date Posted 02/02/2021
Category
Admin-Other Administrative Positions
Employment Type FullTime
Application Deadline Open until filled
 
 
 
 
 

Department:
SOM KC Pathology and Lab Medicine

-----

Pathology & Laboratory Medicine
Position Title:
Post Doctoral Fellow
Job Family Group:
Professional Staff
Job Description Summary:
Postdoctoral scholars at the University of Kansas Medical Center are individuals who have received their terminal degree and who have opted to pursue further training in a postdoctoral appointment. Postdoctoral scholarship is a time-limited appointment, the primary purpose of which is to provide research and/or scholarly training for an academic or research career. A postdoctoral scholar at KUMC is expected to: Participate in a full-time regimen of advanced training and research, train under the supervision of a faculty research mentor who will provide the opportunity for collaborative and independent research, as well promote publication of findings and preparation of research grants as determined by a mutual agreement between the postdoctoral scholar and the mentor, participate in relevant academic activities related to the preparation for a career in research or academia, participate in the University’s Individual Development Plan policy for postdoctoral scholars, have a PhD or equivalent terminal degree (such as MD, DVM, PsyD, PharmD, etc.), and candidates should have strong English skills and demonstrate an ability to write and communicate with a scientific audience. Candidates must be able to independently plan, multi-task and complete projects. Ideally, the fellow will be expected to design and execute experiments, analyze data, write and prepare independent grant applications and manuscripts for scientific publications, and supervise graduate students.
Job Description:
Required Qualifications:
  • Education: PhD in biological sciences

  • Work Experience: Previous experience in cancer (focus will be on epithelial ovarian cancer and potentially gastrointestinal stromal tumor), extracellular vesicles (focused on small EVs) and technical expertise in proteomics and transcriptomics will be a plus.

  • Skills: Strong oral presentation skills in both technical and lay forums. Collaborative and management skills will also be greatly appreciated.


Preferred Qualifications:

  • Education: MD/PhD in biological sciences

  • Work Experience: Expertise in tumor biology and/or molecular cancer genetics and with prior experience in molecular biology techniques, including EV purification and characterization, fluorescent/confocal microscopy (ICC and IHC), EVs labeling and tracking, flow cytometry, protein analysis (Western blot, ELISA and IP), cell culture work, NGS, pRT-PCR, DLS, NTA, Affy microarrays, NanoString ncounter profiling, etc.

  • Skills: Record of initiation and/or participation in successful collaborative research projects. Strong writing skills demonstrated by peer-reviewed publications.


Job Duties Outlined:

  • Develop and validate sEV-based detection system for ovarian cancer early detection and disease monitoring.

  • Establish the proteome of tumor-associated sEVs. Specifically identify unique proteins or distinct pattern of proteins present in sEVs derived from fallopian tube and HGSOC cell lines and tissue explants by mass spectrometry/proteomics; verify the resulting candidate biomarkers by high-throughput capillary-based immunoassays; and Isolate sEVs and analyze by immunoassays and immunoprecipitation to prioritize candidate exo-proteins for the ovarian cancer “fingerprint” that can differentiate HGSOC from controls and other ovarian cancer patients.

  • Establish transcriptome of tumor-associated sEVs. Define EV-associated miRNA signatures that have the greatest stability and reproducibility as analytes to differentiate early-stage ovarian cancer cases from benign disease and healthy controls.

  • Perform research techniques in a laboratory setting, conduct independent research.

  • Work closely with the PI and laboratory members on research projects and in the preparation of data and writing for grants.

  • Write manuscripts for academic publish. Present data to various groups and conferences. Participate in profound collaborations and communications.

  • Assist with overall maintenance of lab.

  • Mentor and direct the work of junior scientists and graduate students.

    • Other duties as assigned.


Required Documents:

  • Resume/CV
  • Cover Letter

Employee Type:
Regular
Time Type:
Full time
Pay Rate Type:
Salary
Pay Grade:
PDF
Pay Range:

Minimum

47476

Midpoint

65352

Maximum

79356

Department:
SOM KC Pathology and Lab Medicine

-----

Pathology & Laboratory Medicine
Position Title:
Post Doctoral Fellow
Job Family Group:
Professional Staff
Job Description Summary:
Postdoctoral scholars at the University of Kansas Medical Center are individuals who have received their terminal degree and who have opted to pursue further training in a postdoctoral appointment. Postdoctoral scholarship is a time-limited appointment, the primary purpose of which is to provide research and/or scholarly training for an academic or research career. A postdoctoral scholar at KUMC is expected to: Participate in a full-time regimen of advanced training and research, train under the supervision of a faculty research mentor who will provide the opportunity for collaborative and independent research, as well promote publication of findings and preparation of research grants as determined by a mutual agreement between the postdoctoral scholar and the mentor, participate in relevant academic activities related to the preparation for a career in research or academia, participate in the University’s Individual Development Plan policy for postdoctoral scholars, have a PhD or equivalent terminal degree (such as MD, DVM, PsyD, PharmD, etc.), and candidates should have strong English skills and demonstrate an ability to write and communicate with a scientific audience. Candidates must be able to independently plan, multi-task and complete projects. Ideally, the fellow will be expected to design and execute experiments, analyze data, write and prepare independent grant applications and manuscripts for scientific publications, and supervise graduate students.
Job Description:
Required Qualifications:
  • Education: PhD in biological sciences

  • Work Experience: Previous experience in cancer (focus will be on epithelial ovarian cancer and potentially gastrointestinal stromal tumor), extracellular vesicles (focused on small EVs) and technical expertise in proteomics and transcriptomics will be a plus.

  • Skills: Strong oral presentation skills in both technical and lay forums. Collaborative and management skills will also be greatly appreciated.


Preferred Qualifications:

  • Education: MD/PhD in biological sciences

  • Work Experience: Expertise in tumor biology and/or molecular cancer genetics and with prior experience in molecular biology techniques, including EV purification and characterization, fluorescent/confocal microscopy (ICC and IHC), EVs labeling and tracking, flow cytometry, protein analysis (Western blot, ELISA and IP), cell culture work, NGS, pRT-PCR, DLS, NTA, Affy microarrays, NanoString ncounter profiling, etc.

  • Skills: Record of initiation and/or participation in successful collaborative research projects. Strong writing skills demonstrated by peer-reviewed publications.


Job Duties Outlined:

  • Develop and validate sEV-based detection system for ovarian cancer early detection and disease monitoring.

  • Establish the proteome of tumor-associated sEVs. Specifically identify unique proteins or distinct pattern of proteins present in sEVs derived from fallopian tube and HGSOC cell lines and tissue explants by mass spectrometry/proteomics; verify the resulting candidate biomarkers by high-throughput capillary-based immunoassays; and Isolate sEVs and analyze by immunoassays and immunoprecipitation to prioritize candidate exo-proteins for the ovarian cancer “fingerprint” that can differentiate HGSOC from controls and other ovarian cancer patients.

  • Establish transcriptome of tumor-associated sEVs. Define EV-associated miRNA signatures that have the greatest stability and reproducibility as analytes to differentiate early-stage ovarian cancer cases from benign disease and healthy controls.

  • Perform research techniques in a laboratory setting, conduct independent research.

  • Work closely with the PI and laboratory members on research projects and in the preparation of data and writing for grants.

  • Write manuscripts for academic publish. Present data to various groups and conferences. Participate in profound collaborations and communications.

  • Assist with overall maintenance of lab.

  • Mentor and direct the work of junior scientists and graduate students.

    • Other duties as assigned.


Required Documents:

  • Resume/CV
  • Cover Letter

Employee Type:
Regular
Time Type:
Full time
Pay Rate Type:
Salary
Pay Grade:
PDF
Pay Range:

Minimum

47476

Midpoint

65352

Maximum

79356
Apply
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